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Novel designs of countercurrent chomatography (CCC) rotors have come out of 
the research of the NIH scientist, Yoichiro Ito.  Spiral disk and spiral tubing rotors are 
capable of retaining the heavy alcohol and 2-phase aqueous solvent systems useful 
for separating large molecules.  Thus proteins can be purified in non-denaturing 
solvents.  This opens up many applications for bio-molecule purification.  From the 
difficult-to-dissolve membrane proteins to the very large modified molecules, labeled 
for delivery or diagnostics, all can now be purified for optimal function.   Spiral CCC 
serves as a versatile tool for the bio-synthetic chemist and chromatographer.  Now all 
types of 2-phase solvent systems can be used to separate all kinds of molecules.

CC Biotech LLC has been established to license the new patents from the NIH 
and is now manufacturing these new rotors for the research laboratory.  We will make 
available the tools and reagents for spiral CCC.  The essential methods and 
applications are available at this website, as well (under continuous development).  If 
there is a question or something else that you need, feel free to contact us.
 
 
 
 
 

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