CCC advantages for biotechnology product purification and analysis
- Liquid flow without expensive columns that wear out; high capacity, low back pressure.
- Less sample loss, good recovery/detection of low conc. components
- Hydrophobic proteins/peptides/lipids separated with high recovery
- Proteins--non-denaturing solvents in purification -- volatile, strong solvents for MS analysis
- Versatile -- affinity, in-line extractions from bioreactors, potential clean-in-place technology for cGMP
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